Investigation on Tautomeric Equilibrium of Schiff Base in Mixed Binary Solvent

Abstract

Enol imine- keto inamine tautomeric equilibrium has been studied in bis-salicilidene schiff base (sal-en-Sal) with a spacer unit in aqueous-organic binary solvent mixture. Organic solvent favors the E-form (enol form) while aqueous solvent favors both the E-form and K-form (keto form). The binary solvent mixture has a transition at almost 70% volume of organic solvent. i.e. the non-aqueous solvent molecules remain within water clusters upto a volume percentage of almost 70, beyond which the water clusters remain in the oil framework. The tautomeric equilibrium is very sensitive to water.