Development of iontophoretic delivery system

Pattnaik, Prasanjeet (2011) Development of iontophoretic delivery system. BTech thesis.



The current study deals with the development of a low-cost iontophoretic delivery system. Iontophoresis deals with the administration of the drug under the influence of electrical potential. A low-cost portable and user friendly pulsed iontophoretic system was developed. The efficiency
of the system, at various duty cycles, was analysed against the salicylic acid (SA)-loaded gelatin gels. The current density for the studies was maintained at 0.5 mA/cm2. The results indicated that as the duty cycle was increased there was a subsequent increase in the drug release from the
gelatin gels. 100 % duty cycle provided the best release behaviour in terms of % SA release. Taking this as the reference duty cycle, the SA release from the alginate-gelatin and chitosangelatin gels were also studied. The results indicated that as the proportion of alginate was
increased in the alginate-gelatin gels, there was an increase in the % release whereas there was a decrease in the SA release as the chitosan proportion was increased in the chitosan-gelatin gels. The release patterns indicated that the release from the gels followed Higuchian kinetics.

Item Type:Thesis (BTech)
Uncontrolled Keywords:Iontophoresis, Electric Potential, Current density, Higuchian kinetics
Subjects:Engineering and Technology > Biomedical Engineering
Divisions: Engineering and Technology > Department of Biotechnology and Medical Engineering
ID Code:2484
Deposited By:Mr Prasanjeet Pattnaik
Deposited On:16 May 2011 17:30
Last Modified:15 Jun 2012 08:38
Supervisor(s):Pal, K

Repository Staff Only: item control page