Modification of collector of Electro spinning Machine for the fabrication of 3-D nanofibrous scaffold for Tissue Engineering applications

Abstract

The present work deals with the modification of collector system of the existing Free liquid surface type electrospinning machine to prepare 3-D Nanofibrous scaffold. Initially the trial has been given to prepare 2-D electrospun nanofibers using PVA polymer solution. To make 3-D nanofibrous scaffold, a cylindrical pipe made up of plastic material with required diameter was introduced as the collector. A motor attached to the collector to rotate at its horizontal axis thus acting as a guide to the charged polymer jet to let it deposit around its curved surface area. The cylindrical-shaped nanofibrous PVA scaffolds were then prepared that can be useful for tissue engineering application especially in the development of vascular blood vessels implant.