Preparation and characterization of poly vinyl alcohol - gelatin- carboxy methyl chitosan polymer films

Abstract

Present work delineate the preparation and characterization of polymer films of polyvinyl alcohol (PVA), gelatin and carboxy methyl chitosan. The films were prepared by esterification followed by glutaraldehyde crosslinking. Swelling behaviour and biodegradability of the polymer films were studied at physiological pH. Further, hemocompatibility and biocompatibility of the polymer film was also evaluated. Result showed that films of different composition have water-swelling capacity around 80%. Biodegradation study revealed that 35% degradation could be achieved by varying the composition. All the polymeric films were found hemocompatible and biocompatible. From this preliminary study it can be said that such films could be used for biomedical application.