Ocular impants: formation and characterisation

Singh, D (2014) Ocular impants: formation and characterisation. BTech thesis.



The eye presents remarkable open doors and difficulties regarding the matter of the transport of Pharmaceuticals. While ingestion by this course is botching, there are few symptoms with routine visual dose structures like the eye drop and the eye suspension. A few polymeric frameworks have been utilized to create visual supplements for the better visual bioavailability and maintenance of medication for which the gelling frameworks have indicated focal points of advantageous organization and expanded contact time. Solvent casting technique was used for preparing PVP/PVA ocular inserts. The arranged ocular inserts were portrayed by method for film thickness, weight variety, collapsing persistence Value, XRD, DSC, SEM. These days, the utilization of polymers in therapeutic requisitions blankets an expansive assorted qualities of fields including inserts, prostheses, ophthalmology, dentistry and bone repair; they assume an imperative part as a provisional framework, a makeshift obstruction, and a medication conveyance framework. Poly(vinyl pyrrolidone) (PVP) and poly(vinyl Alcohol) (PVA) are incorporated in the rundown of engineered polymers which are utilized as a part of solution. PVP has a great notoriety because of its remarkable assimilation and buildings capacities, inasmuch as PVA presents imperative characteristics, for example, high hydrophilicity, perceived biodegradability, biocompatibility and great processability in film form shaping. In addition, these manufactured polymers are water dissolvable which is an exceptional trademark for film framing.

Item Type:Thesis (BTech)
Uncontrolled Keywords:Ocular inserts; PVA; PVP; Hemocompatibility; Swelling; XRD; Film
Subjects:Engineering and Technology > Biomedical Engineering
Divisions: Engineering and Technology > Department of Biotechnology and Medical Engineering
ID Code:6248
Deposited By:Hemanta Biswal
Deposited On:08 Sep 2014 11:48
Last Modified:08 Sep 2014 11:48
Supervisor(s):Gupta, M K

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