Evaluation of Antioxidant and Anticancer Efficacy of Chitosan Based Nanoparticles

Abstract

Synthesis of chitosan based nanoparticle is a novel way for synthesis of nanoparticles by using biological sources. It is gaining attention due to its cost effective, ecofriendly and large scale production possibilities. In the present study six formulations are made taking chitosan as base material: chitosan-ascorbic acid(Cs-Aa), chitosan-ascorbic acid-Glucose(Cs-Aa-Glu), chitosan-Polyethyl glycol (Cs-PEG), chitosan-vitamin E (Cs-Vitamin E),chitosan-catechol (Cs-Cat),chitosan-Silver nanoparticles (Cs-AgNp)were taken to investigate their antioxidant property. The appearance of milky white solution indicates that nanoparticles are being formed. The characterization studied was done by UV-Visible spectroscopy, Scanning Electron Microscopy (SEM), Dynamic Light Scattering (DLS) and zeta potential studies, X-Ray diffraction (XRD), Fourier Transmission Infrared Spectroscopy (FTIR).