Evaluation of Antioxidant and Anticancer Efficacy of Chitosan Based Nanoparticles

Minz, Aliva Prity (2015) Evaluation of Antioxidant and Anticancer Efficacy of Chitosan Based Nanoparticles. MSc thesis.



Synthesis of chitosan based nanoparticle is a novel way for synthesis of nanoparticles by using biological sources. It is gaining attention due to its cost effective, ecofriendly and large scale production possibilities. In the present study six formulations are made taking chitosan as base material: chitosan-ascorbic acid(Cs-Aa), chitosan-ascorbic acid-Glucose(Cs-Aa-Glu), chitosan-Polyethyl glycol (Cs-PEG), chitosan-vitamin E (Cs-Vitamin E),chitosan-catechol (Cs-Cat),chitosan-Silver nanoparticles (Cs-AgNp)were taken to investigate their antioxidant property. The appearance of milky white solution indicates that nanoparticles are being formed. The characterization studied was done by UV-Visible spectroscopy, Scanning Electron Microscopy (SEM), Dynamic Light Scattering (DLS) and zeta potential studies, X-Ray diffraction (XRD), Fourier Transmission Infrared Spectroscopy (FTIR).

Item Type:Thesis ( MSc)
Uncontrolled Keywords:antioxidant, chitosan nanoparticles, cell viability, ROS
Subjects:Life Science > Immunology
Divisions: Sciences > Department of Life Science
ID Code:7573
Deposited By:Mr. Sanat Kumar Behera
Deposited On:24 May 2016 12:47
Last Modified:24 May 2016 12:47
Supervisor(s):Nayak, B

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