Fabrication and Characterization of PVA-PVP Based Ocular Film

Abstract

The eye is standout amongst the most sensitive and complex organs in body,which makes vision possible. Cataract surgery is one of the most common surgeries performed. So after cataract ocular lens is needed for correcting eye power. In this work wehave used PVA--PVPblends to develop ocular film. Films were cross-linked by freeze thawing process and solvent evaporation. We have prepared films of five different concentrations named S1-S5. As per FTIR S3 S4 have better FTIR peaks. They have refractive index between ranges of 1.75-1.9. They have shown good complex modulus reading during rheological study which was comparable with human crystalline lens. Folding endurance has how flexibility increases with PVP. XRD was performed to check crystallinity, SEM and Mechanical testing was performed to measure strength and Youngs modulus. We have also performed haemocompatibility degradation study and got favorable result. Finally we can conclude that it may be used as contact lens purpose